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The Lost Sea, Craighead Caverns

Tennessee

Inside a Tennessee mountain at Sweetwater lies the largest underground lake in America, so big they float it in glass-bottom boats over the trout. The cave was used by the Cherokee and by Confederate saltpeter miners, and a rare crystal called anthodite grows in its far rooms. A real underground lake you sail on.

Where it is

Tennessee
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The source

https://en.wikipedia.org/wiki/Craighead_Caverns

Nearby

Other places on the map within a couple of hours.